May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies).

推荐稀释比 WB:1/500-1/1000;IF:1:50/1:200

Western blot analysis of Phospho-alpha Synuclein (Tyr136) in mouse brain lysates using aSynuclein (Phospho-Tyr136) antibody and the same antibody preincubated with blocking peptide.

Immunofluorescence analysis of Phospho-alpha Synuclein (Tyr136) in Hela using alpha Synuclein (Phospho-Tyr136) antibody.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.