Catenin δ-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function. Catenin δ-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion.

推荐稀释比 IHC:1/100-1/200

Immunohistochemistry analysis of paraffin-embedded Breast using delta 1 Catenin antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

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