PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]

推荐稀释比 FC:1/50-1/100;ELISA:1/10000

Flow Cytometry analysis of Hela cells using PAX2 antibody (green) and negative control (red).

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.