Purity:SDS-PAGE

Anti-ERBB2 / HER2 / CD340 Reference Antibody (pertuzumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.

Purity:SEC-HPLC

The purity of Anti-ERBB2 / HER2 / CD340 Reference Antibody (pertuzumab) is 99.02%, determined by SEC-HPLC.

Bioactivity:ELISA

Immobilized human HER2(23 652) His at 2 ug/mL can bind Anti-ERBB2 / HER2 / CD340 Reference Antibody (pertuzumab), EC50=0.01375 ug/mL.

Bioactivity:FACS

BT474 cells were stained with Anti-ERBB2 / HER2 / CD340 Reference Antibody (pertuzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.2994 ug/mL.

Research in vivo

Pertuzumab+trastuzumab inhibited the tumor growth of NCI-N87 on Balb/c nude mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 73.8% at 5 mpk at D37.

-25~-15℃保存，有效期1年。